Abstract: International cooperation has long been founded on the idea that securing a common factual understanding of things in the world is a prerequisite for deciding how to act in concert. However, in recent decades the very possibility of such agreement on the facts has come under attack both empirically, through persistent technical controversies around issues such as climate change and crop biotechnology, and theoretically, from demonstrations that facts and norms are co-produced to build alternate, coexisting worlds. The divergent self-understandings of these worlds, in which epistemic and normative order are interdependent, cannot be bridged by simply insisting on a singular “reality” that must be accepted by all.

In this talk, I use the longue durée case of international biotech regulation to suggest a different basis for long-term cooperation. Using epistemic subsidiarity rather than harmonization as the basis for making progress, I suggest how biotechnology risks might be handled in three regimes of subsidiarity: coexistence, cosmopolitanism, and constitutionalism. The advantages and limits of each regime will be exemplified and reflected upon.

Speaker bio: Sheila Jasanoff is Pforzheimer Professor of Science and Technology Studies at the Harvard Kennedy School. A pioneer in her field, she has authored more than 120 articles and chapters and is author or editor of more than 15 books, including The Fifth Branch, Science at the Bar, Designs on Nature, and The Ethics of Invention. Her work explores the role of science and technology in the law, politics, and policy of modern democracies. She founded and directs the STS Program at Harvard; previously, she was founding chair of the STS Department at Cornell. She has held distinguished visiting appointments at leading universities in Europe, Asia, Australia, and the US. Jasanoff served on the AAAS Board of Directors and as President of the Society for Social Studies of Science. She is a member of the Council on Foreign Relations. Her honors include a Guggenheim Fellowship, an Ehrenkreuz from the Government of Austria, membership in the Royal Danish Academy, and the Humboldt Foundation’s Reimar-Lüst award. She holds AB, JD, and PhD degrees from Harvard, and honorary doctorates from the Universities of Twente and Liège.

Abstract: Against a backdrop of emerging and reemerging infectious diseases of natural origin, fueled by changes in land use and global climate, there is an ongoing revolution in the life sciences with growing empowerment of the individual to decipher, genetically alter, and manufacture living things. In addition to widely-touted potential benefits, these events and developments pose challenges and risks of profound harm to humans and the rest of the planet. Yet, the United States and most other nations have failed to respond with a strategic plan, sustained resources, coherent leadership, critical self-assessment, and accountability. Why is this? A selected history of recent naturally-occurring disease outbreaks and advances in the life sciences that create new risks of potential misuse will be offered, differing perspectives from the science and policy communities described, and some of the efforts to address these challenges summarized. Forward-looking proposals for efforts to mitigate risk in the life sciences will be discussed.

Speaker Bio: David A. Relman, M.D., is the Thomas C. and Joan M. Merigan Professor in Medicine, and Microbiology & Immunology at Stanford University, and Chief of Infectious Diseases at the Veterans Affairs Palo Alto Health Care System. He is also Senior Fellow at the Freeman Spogli Institute for International Studies (FSI), and served as science co-director at the Center for International Security and Cooperation from 2013-2017. He is currently director of a new Biosecurity Initiative at FSI.

Relman identified several historically important and novel microbial disease agents, and was an early pioneer in the modern study of the human indigenous microbiota (microbiome). His lab group currently examines human microbial community assembly, and community stability and resilience.

Among policy-relevant activities, Relman is currently a member of the Intelligence Community Studies Board at the National Academies of Science (NAS), served as vice-chair of the NAS Committee that reviewed the science performed for the FBI 2001 Anthrax Letters investigation, and was a member of the National Science Advisory Board on Biosecurity. He was elected to the National Academy of Medicine in 2011. 

Abstract: The threat of biological catastrophes-- stemming from natural, accidental or intentional causes-- looms ever larger as populations urbanize, global temperatures rise, and the access to biological weapons spreads. In fact, climate change and the increasing ease with which biological weapons may be obtained represent two significant threats to public health. As these threats materialize, they test nations’ resources, capabilities, and strength. Through an examination of the policy and scientific challenges posed by weaponized biological agents as well as by the growing public health risks stemming from climate change impacts, key gaps in bio-preparedness emerge. Bio-preparedness efforts, nationally and globally, do not currently keep pace with emerging biological risks. Will the scientific and policy communities find common ground to move the global health agenda forward through prevention, detection, and response?

Speaker Bio: Alice Hill is a Research Fellow at the Hoover Institution at Stanford University.  She previously served at the White House as Special Assistant to President Barack Obama and Senior Director for Resilience Policy on the National Security Council.  Hill led the creation of national policy regarding catastrophic risk, including the impacts of climate change and biological threats.

Hill previously served as Senior Counselor to the Secretary of the Department of Homeland Security (DHS).  She headed the DHS Biological Leadership group and led development of Department strategies and policies regarding catastrophic biological and chemical incidents, ranging from pandemics to weapons of mass destruction.  Hill also founded and was the first Chair of the Blue Campaign, an internationally recognized anti-human trafficking campaign.

Earlier in her career, Hill has served as a supervising judge on the Los Angeles Superior Court and as chief of the white-collar crime unit in the Los Angeles US Attorney’s Office.

She is a frequent speaker and has been quoted in the NY Times, Washington Post, and Los Angeles Times, among other publications. She has appeared on CBS, NPR, and MSNBC and her commentary has been published in Newsweek, LawFare, The Hill, and other media.  She has received numerous awards and commendations, including the Department of Justice’s highest award for legal accomplishment, Harvard’s Meta-Leader of the Year Award, and the San Fernando Valley Bar’s Judge of the Year.

Abstract: High-security organizations around the world face devastating threats from insiders—trusted employees with access to sensitive information, facilities, and materials. From Edward Snowden to the Fort Hood shooter to the theft of nuclear materials, the threat from insiders is on the front page and at the top of the policy agenda. Insider Threats offers detailed case studies of insider disasters across a range of different types of institutions, from biological research laboratories, to nuclear power plants, to the U.S. Army. Matthew Bunn and Scott D. Sagan outline cognitive and organizational biases that lead organizations to downplay the insider threat, and they synthesize "worst practices" from these past mistakes, offering lessons that will be valuable for any organization with high security and a lot to lose.

About the Speakers: Matthew Bunn is a Professor of Practice at Harvard University's John F. Kennedy School of Government. His research interests include nuclear theft and terrorism; nuclear proliferation and measures to control it; the future of nuclear energy and its fuel cycle; and policies to promote innovation in energy technologies. Before joining the Kennedy School in January 1997, he served for three years as an adviser to the Office of Science and Technology Policy, where he played a major role in U.S. policies related to the control and disposition of weapons-usable nuclear materials in the United States and the former Soviet Union, and directed a secret study for President Clinton on security for nuclear materials in Russia.

Scott S. Sagan is the Caroline S.G. Munro Professor of Political Science, the Mimi and Peter Haas University Fellow in Undergraduate Education, and Senior Fellow at the Center for International Security and Cooperation and the Freeman Spogli Institute at Stanford University. He also serves as Project Chair for the American Academy of Arts and Sciences’ Initiative on New Dilemmas in Ethics, Technology, and War. Before joining the Stanford faculty, Sagan was a lecturer in the Department of Government at Harvard University. From 1984 to 1985, he served as special assistant to the director of the Organization of the Joint Chiefs of Staff in the Pentagon. Sagan has also served as a consultant to the office of the Secretary of Defense and at the Sandia National Laboratory and the Los Alamos National Laboratory. 

Amy Zegart is is co-director of CISAC and Professor of Political Science, by courtesy. She is also the Davies Family Senior Fellow at the Hoover Institution. 

- The book, Insider Threats, will be available for purchase at the event -