Aging
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Two studies examined age differences in recall and recognition memory for positive, negative, and neutral stimuli. In Study 1, younger, middle-aged, and older adults were shown images on a computer screen and, after a distraction task, were asked first to recall as many as they could and then to identify previously shown images from a set of old and new ones. The relative number of negative images compared with positive and neutral images recalled decreased with each successively older age group. Recognition memory showed a similar decrease with age in the relative memory advantage for negative pictures. In Study 2, the largest age differences in recall and recognition accuracy were also for the negative images. Findings are consistent with socioemotional selectivity theory, which posits greater investment in emotion regulation with age.

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Journal of Personality and Social Psychology
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One in eight Americans today is over the age of 65, and the proportion will increase dramatically in the future. The aging of the population has begun to drive tax and budget decisions and the federal policy agenda, as policy makers and voters look ahead to enormous demands on the health and income security programs. Indeed, it is projected that Medicare and Social Security will constitute nearly half the federal budget in the year 2030, when one in five Americans will be over 65. In Policies for an Aging Society, Stuart H. Altman and David I. Shactman have gathered experts in public and health policy, economics, law, and management to identify the salient issues and explore realistic options. From positions ranging from liberal to conservative, the contributors take a wide view of the philosophical, economic, and programmatic aspects of the social protection programs for elderly Americans. They ask broad questions and propose integrated conceptions of how our society can best provide for the needs of its aging population.

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Johns Hopkins Press in "Policies for an Aging Society: Confronting the Economic and Political Challenges", edited by Stuart B Altman and David Shactman
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BACKGROUND: Patients with end-stage renal disease are known to have decreased survival after myocardial infarction, but the association of less severe renal dysfunction with survival after myocardial infarction is unknown.

OBJECTIVES: To determine how patients with renal insufficiency are treated during hospitalization for myocardial infarction and to determine the association of renal insufficiency with survival after myocardial infarction.

DESIGN: Cohort study.

SETTING: All nongovernment hospitals in the United States.

PATIENTS: 130 099 elderly patients with myocardial infarction hospitalized between April 1994 and July 1995.

MEASUREMENTS: Patients were categorized according to initial serum creatinine level: no renal insufficiency (creatinine level < 1.5 mg/dL [<132 micromol/L]; n = 82 455), mild renal insufficiency (creatinine level, 1.5 to 2.4 mg/dL [132 to 212 micromol/L]; n = 36 756), or moderate renal insufficiency (creatinine level, 2.5 to 3.9 mg/dL [221 to 345 micromol/L]; n = 10 888). Vital status up to 1 year after discharge was obtained from Social Security records.

RESULTS: Compared with patients with no renal insufficiency, patients with moderate renal insufficiency were less likely to receive aspirin, beta-blockers, thrombolytic therapy, angiography, and angioplasty during hospitalization. One-year mortality was 24% in patients with no renal insufficiency, 46% in patients with mild renal insufficiency, and 66% in patients with moderate renal insufficiency (P < 0.001). After adjustment for patient and treatment characteristics, mild (hazard ratio, 1.68 [95% CI, 1.63 to 1.73]) and moderate (hazard ratio, 2.35 [CI, 2.26 to 2.45]) renal insufficiency were associated with substantially elevated risk for death during the first month of follow-up. This increased mortality risk continued until 6 months after myocardial infarction.

CONCLUSIONS: Renal insufficiency was an independent risk factor for death in elderly patients after myocardial infarction. Targeted interventions may be needed to improve treatment for this high-risk population.

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Annals of Internal Medicine
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Survival of patients who sustain a ventricular arrhythmia is poor but slowly improving due to in-hospital use of medications and ICDs. However, this more intensive hospital treatment has been accompanied by increased hospital expenditures, finds this study. The researchers analyzed Medicare databases from 1985 to 1995 to identify elderly patients hospitalized with ventricular arrhythmias (index admission). They created a longitudinal patient profile by linking the index hospital admission with all earlier and subsequent admissions and with death records.

During this time, about 85,000 elderly patients went to U.S. emergency departments (EDs) with ventricular arrhythmias each year. Only about 20,000 of these patients lived to be admitted to the hospital from the ED, and then about 14 percent died within the first day. From 1987 to 1995, the demographic and clinical characteristics of patients and the use of coronary angioplasty and bypass graft surgery for these patients were largely unchanged. However, the use of electrophysiology studies (EPS) grew from 3 to 22 percent and use of ICDs increased from 1 to 13 percent. A growing number of patients survived, particularly in the medium term, with 1-year survival rates increasing from 53 percent in 1987 to 58 percent in 1994, or half a percentage point each year.

At the same time, hospital expenditures rose 8 percent per year, primarily because of the increased use of EPS and ICD procedures. By 1993, Medicare was reimbursing hospitals an average of $15,627 for care for each patient during the year after admission for ventricular tachycardia/fibrillation. During the subsequent year, another $14,739 on average was spent for these patients. The increased intensity of care for these patients led to a rise in the average expenditure per patient of about $1,000 per year (in 1993 dollars) from 1987 to 1995.

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American Heart Journal
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Mark A. Hlatky
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OBJECTIVE: To investigate recent national trends in nonsteroidal antiinflammatory drug (NSAID) and acetaminophen use for osteoarthritis (OA).

METHODS: Using data from the 1989-98 National Ambulatory Medical Care Survey, a representative sample of US office based physician visits, we assessed 4471 visits by patients 45 years or older with a diagnosis of OA. We examined cross sectional and longitudinal patterns of OA pharmacotherapy. The independent effects of patient and physician characteristics on NSAID and acetaminophen use were examined using multiple logistic regression analysis.

RESULTS: Pharmacological treatment for OA (either NSAID, acetaminophen, or both) has steadily decreased from 49% of visits (1989-91) to 46% (1992-94) to 40% (1995-98) (p = 0.001). Reduced NSAID use over this time period (46% to 33%; p = 0.001) was partially offset by a modest increase in acetaminophen use (5% to 10%; p = 0.001). Among individual NSAID, ibuprofen (5.7% of OA visits), nabumetone (4.9%), naproxen (4.6%), and aspirin (4.4%) were the most frequently reported in 1995-98. For patient visits in 1995-98, 45 to 59-year-olds (38%) received NSAID more often than 60 to 74-year-olds (34%) or patients older than 75 (28%; p = 0.029). Other possible predictors of OA therapy included patient race and physician specialty.

CONCLUSION: The decline in the use of NSAID from 1989 to 1998, especially among elderly patients, and the frequent selection of safer medications may reflect awareness of the literature citing the risks of nonsteroidals for OA. However, variations in prescribing patterns among different patient populations and the modest use of acetaminophen, despite evidence supporting its efficacy, suggest that better assimilation of the literature into medical practice is needed to optimize OA therapy.

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Journal of Rheumatology
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Lin Shu-ya will discuss the Taiwanese government's reserved land policy that is aimed at aiding indigenous people to be self-sufficient and integrate into mainstream society. This policy has been the main government policy for 50 years even though Ms. Lin argues that collective management might be a better option for the indegenous communities, allowing them to collectively manage their traditional territory. Varamon Ramangkura will discuss te impact of recent WTO free-trade versus the environment disputes on industry in Thailand. Ms Ramangkura will show that pressure from the WTO on the Thai government is forcing the closure of local shrimp farms and reducing the sustainability of this industry in Thailand. Shimamura Kazuyuki will analyze the problems of the land use system in Japan. Even after recent reforms in land use, the municipalities enact undemocratic, informal and opaque local ordinances for land use. Mr. Shimamura argues that the reforms must be adopted by the local governments and made fiscally transparent, be based on the needs of the citizens and that there is a necessity to create a legal foundation for broader delegation, particularly regarding the comprehensive planning system at the municipality level.

Okimoto Conference Room, Encina Hall, third floor, east wing

Lin Shu-ya Fellow Stanford Program in International Legal Studies
Varamon Ramangkura Fellow Stanford Program in International Legal Studies
Shimamura Kazuyuki Fellow Stanford Program in International Legal Studies
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Professor Campbell will discuss Japan's new public, mandatory, long-term care insurance program: does it make sense as social policy? As economic policy? Professor Creighton has long been interested in the relationship between politics and substantive public policy, and in the way policies change upon implementation. He has pursued this interest mostly in the context of the Japanese political system, and in this talk he will apply his framework to Japan's foray into socialized care for the elderly.

Okimoto Conference Room, Third Floor, East Wing, Encina Hall

John Creighton Campbell Professor of Political Science Speaker University of Michigan
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PURPOSE: To determine if greater managed care market share is associated with greater use of recommended therapies for fee-for-service patients with acute myocardial infarction.

SUBJECTS AND METHODS: We examined the care of 112,900 fee-for-service Medicare beneficiaries aged > or = 65 years who resided in one of 320 metropolitan statistical areas and who were admitted with an acute myocardial infarction between February 1994 through July 1995. Use of recommended medical treatments and 30-day survival were determined for areas with low (<10%), medium (10% to 30%), and high (>30%) managed care market share.

RESULTS: After adjustment for severity of illness, teaching status of the admission hospital, and area characteristics, areas with high levels of managed care had greater use of beta-blockers (relative risk [RR] for greater use = 1.18; 95% confidence interval [CI]: 1.06 to 1.29) and aspirin at discharge (RR = 1.05; 95% CI: 1.02 to 1.07), but less appropriate coronary angiography (RR = 0.93; 95% CI: 0.86 to 1.01) and reperfusion (RR = 0.95; 95% CI: 0.85 to 1.03) when compared with areas with low levels of managed care.

CONCLUSIONS: Medicare beneficiaries with fee-for-service insurance who resided in areas with high managed care activity were more likely to have received appropriate treatment with beta-blockers and aspirin, and less likely to have undergone coronary angiography following admission for myocardial infarction. Thus, the effects of managed care may not be limited to managed care enrollees.

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The American Journal of Medicine
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Laurence C. Baker
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